5/17/2025
Last update
5/17/2025
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.4
USERS' SCORE
Good
Based on 4 Reviews
8.2
Supplement Facts
Serving Size: 2 Veg Capsules
Amount Per Serving
%DV
Magnesium (from Magnesium Aspartate)
250 mg
60%
Potassium (from Potassium Aspartate)
99 mg
2%
Taurine (Free-Form)
100 mg
†
Top Medical Research Studies
9
Gitelman syndrome impacts infant development
We examined a unique case of an 18-month-old boy diagnosed with Gitelman syndrome, a rare condition leading to developmental delays.
His symptoms included psychomotor retardation and low potassium levels. Genetic tests confirmed mutations in the SLC12A3 gene, responsible for this condition.
After oral potassium supplementation, we observed remarkable improvement in his potassium levels and developmental progress. This case highlights the importance of recognizing Gitelman syndrome in young children with growth and developmental issues, as early treatment can lead to positive outcomes.
His symptoms included psychomotor retardation and low potassium levels. Genetic tests confirmed mutations in the SLC12A3 gene, responsible for this condition.
After oral potassium supplementation, we observed remarkable improvement in his potassium levels and developmental progress. This case highlights the importance of recognizing Gitelman syndrome in young children with growth and developmental issues, as early treatment can lead to positive outcomes.
Read More
8
Magnesium potentially benefits CFS patients
We investigated the relationship between magnesium levels in red blood cells and chronic fatigue syndrome (CFS). A case-control study revealed that CFS patients had lower magnesium levels than healthy individuals.
In a randomized, double-blind trial, 32 CFS patients received either magnesium sulphate or a placebo for six weeks. Those treated with magnesium reported significant improvements in energy, emotional wellbeing, and pain relief, with twelve out of fifteen feeling better.
In contrast, only three out of seventeen patients on placebo reported any improvement. Overall, these findings suggest that magnesium treatment may positively impact the wellbeing of those suffering from CFS.
In a randomized, double-blind trial, 32 CFS patients received either magnesium sulphate or a placebo for six weeks. Those treated with magnesium reported significant improvements in energy, emotional wellbeing, and pain relief, with twelve out of fifteen feeling better.
In contrast, only three out of seventeen patients on placebo reported any improvement. Overall, these findings suggest that magnesium treatment may positively impact the wellbeing of those suffering from CFS.
Read More
7
We aimed to understand the effects of magnesium sulfate treatment on a patient with chronic fatigue syndrome. The case involved a 29-year-old woman experiencing severe fatigue alongside various symptoms, including swelling lymph nodes and muscle pain.
After other treatments failed to provide relief, we administered magnesium sulfate intravenously once a week. Remarkably, after six weeks, the patient reported a significant reduction in fatigue and improved daily functioning, eventually leading to her discharge from the hospital.
After other treatments failed to provide relief, we administered magnesium sulfate intravenously once a week. Remarkably, after six weeks, the patient reported a significant reduction in fatigue and improved daily functioning, eventually leading to her discharge from the hospital.
Read More
Most Useful Reviews
9
Chronic fatigue relief
1 people found this helpful
I take metipred, thus needing to replenish potassium. I consume 2 capsules at night, and thanks to magnesium, my chronic fatigue has vanished.
Read More
7.5
Positive fatigue impact
246 people found this helpful
Magnesium aspartate possesses increased bioavailability. Clinical trials from the 1960s indicated that the combination of magnesium and potassium aspartates positively affects fatigue and reduces muscle hyperexcitability. This form is often used for chronic fatigue syndrome. I highly recommend purchasing it!
Read More
7.5
Well-researched effectiveness
6 people found this helpful
I recommend this for purchase due to its excellent balance. Magnesium aspartate has high bioavailability. As established in clinical trials from the 60s, combining magnesium and potassium aspartates benefits fatigue and reduces muscle hyperexcitability. This supplement is frequently recommended for chronic fatigue syndrome.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.4
- All Researches
10
We investigated the impact of potassium arsenite on chronic fatigue syndrome (CFS) in two veterinary professionals. After struggling with CFS despite various treatments, they turned to a low dosage of potassium arsenite for ten days. Remarkably, both experienced a complete remission of their symptoms, and follow-up tests showed a notable improvement, including the disappearance of the bacteria from their blood.
While this suggests a potential link between bacterial infections and CFS, it's important to note that broader implications for treatment require more extensive research. This case prompts intriguing questions about the role of infections and alternative therapies in managing CFS.
While this suggests a potential link between bacterial infections and CFS, it's important to note that broader implications for treatment require more extensive research. This case prompts intriguing questions about the role of infections and alternative therapies in managing CFS.
Read More
9
Gitelman syndrome impacts infant development
We examined a unique case of an 18-month-old boy diagnosed with Gitelman syndrome, a rare condition leading to developmental delays.
His symptoms included psychomotor retardation and low potassium levels. Genetic tests confirmed mutations in the SLC12A3 gene, responsible for this condition.
After oral potassium supplementation, we observed remarkable improvement in his potassium levels and developmental progress. This case highlights the importance of recognizing Gitelman syndrome in young children with growth and developmental issues, as early treatment can lead to positive outcomes.
His symptoms included psychomotor retardation and low potassium levels. Genetic tests confirmed mutations in the SLC12A3 gene, responsible for this condition.
After oral potassium supplementation, we observed remarkable improvement in his potassium levels and developmental progress. This case highlights the importance of recognizing Gitelman syndrome in young children with growth and developmental issues, as early treatment can lead to positive outcomes.
Read More
8
Magnesium potentially benefits CFS patients
We investigated the relationship between magnesium levels in red blood cells and chronic fatigue syndrome (CFS). A case-control study revealed that CFS patients had lower magnesium levels than healthy individuals.
In a randomized, double-blind trial, 32 CFS patients received either magnesium sulphate or a placebo for six weeks. Those treated with magnesium reported significant improvements in energy, emotional wellbeing, and pain relief, with twelve out of fifteen feeling better.
In contrast, only three out of seventeen patients on placebo reported any improvement. Overall, these findings suggest that magnesium treatment may positively impact the wellbeing of those suffering from CFS.
In a randomized, double-blind trial, 32 CFS patients received either magnesium sulphate or a placebo for six weeks. Those treated with magnesium reported significant improvements in energy, emotional wellbeing, and pain relief, with twelve out of fifteen feeling better.
In contrast, only three out of seventeen patients on placebo reported any improvement. Overall, these findings suggest that magnesium treatment may positively impact the wellbeing of those suffering from CFS.
Read More
7
We investigated how magnesium levels relate to chronic fatigue by studying 93 patients with unexplained fatigue.
Around 47% of participants showed magnesium deficiency, linked to reduced plasma antioxidant capacity.
Although magnesium supplementation didn't increase blood glutathione levels, we observed improved magnesium stores and vitamin E levels.
However, this did not equate to a significant boost in antioxidant activity or a decrease in lipid vulnerability. Therefore, while magnesium may help improve some parameters, it is not a panacea for chronic fatigue syndrome.
Around 47% of participants showed magnesium deficiency, linked to reduced plasma antioxidant capacity.
Although magnesium supplementation didn't increase blood glutathione levels, we observed improved magnesium stores and vitamin E levels.
However, this did not equate to a significant boost in antioxidant activity or a decrease in lipid vulnerability. Therefore, while magnesium may help improve some parameters, it is not a panacea for chronic fatigue syndrome.
Read More
7
We aimed to understand the effects of magnesium sulfate treatment on a patient with chronic fatigue syndrome. The case involved a 29-year-old woman experiencing severe fatigue alongside various symptoms, including swelling lymph nodes and muscle pain.
After other treatments failed to provide relief, we administered magnesium sulfate intravenously once a week. Remarkably, after six weeks, the patient reported a significant reduction in fatigue and improved daily functioning, eventually leading to her discharge from the hospital.
After other treatments failed to provide relief, we administered magnesium sulfate intravenously once a week. Remarkably, after six weeks, the patient reported a significant reduction in fatigue and improved daily functioning, eventually leading to her discharge from the hospital.
Read More
User Reviews
USERS' SCORE
Good
Based on 4 Reviews
8.2
- All Reviews
- Positive Reviews
- Negative Reviews
9
Chronic fatigue relief
1 people found this helpful
I take metipred, thus needing to replenish potassium. I consume 2 capsules at night, and thanks to magnesium, my chronic fatigue has vanished.
Read More
7.5
Positive fatigue impact
246 people found this helpful
Magnesium aspartate possesses increased bioavailability. Clinical trials from the 1960s indicated that the combination of magnesium and potassium aspartates positively affects fatigue and reduces muscle hyperexcitability. This form is often used for chronic fatigue syndrome. I highly recommend purchasing it!
Read More
7.5
Well-researched effectiveness
6 people found this helpful
I recommend this for purchase due to its excellent balance. Magnesium aspartate has high bioavailability. As established in clinical trials from the 60s, combining magnesium and potassium aspartates benefits fatigue and reduces muscle hyperexcitability. This supplement is frequently recommended for chronic fatigue syndrome.
Read More
7.5
Fatigue and cramps relief
This product is an excellent assistant, balancing electrolytes and helping to alleviate fatigue, headaches, swelling, and cramps. It aids recovery after intense workouts and promotes sleep. I regularly keep it on hand for constant use.
Read More
Frequently Asked Questions
9
Chronic fatigue relief
1 people found this helpful
I take metipred, thus needing to replenish potassium. I consume 2 capsules at night, and thanks to magnesium, my chronic fatigue has vanished.
7.5
Fatigue and cramps relief
This product is an excellent assistant, balancing electrolytes and helping to alleviate fatigue, headaches, swelling, and cramps. It aids recovery after intense workouts and promotes sleep. I regularly keep it on hand for constant use.
7.5
Positive fatigue impact
246 people found this helpful
Magnesium aspartate possesses increased bioavailability. Clinical trials from the 1960s indicated that the combination of magnesium and potassium aspartates positively affects fatigue and reduces muscle hyperexcitability. This form is often used for chronic fatigue syndrome. I highly recommend purchasing it!
7.5
Well-researched effectiveness
6 people found this helpful
I recommend this for purchase due to its excellent balance. Magnesium aspartate has high bioavailability. As established in clinical trials from the 60s, combining magnesium and potassium aspartates benefits fatigue and reduces muscle hyperexcitability. This supplement is frequently recommended for chronic fatigue syndrome.
4
We systematically reviewed randomized controlled trials on complementary and alternative medicine (CAM) treatments for chronic fatigue syndrome (CFS).
Although 26 studies involving over 3,000 participants explored various therapies, the findings showed limited effectiveness overall.
While some treatments like massage and specific dietary supplements had some positive effects, most failed to provide significant benefits.
Notably, magnesium showed potential, but due to small sample sizes and biases in the studies, we can't make firm conclusions just yet. More rigorous studies are needed to confirm these effects.
Although 26 studies involving over 3,000 participants explored various therapies, the findings showed limited effectiveness overall.
While some treatments like massage and specific dietary supplements had some positive effects, most failed to provide significant benefits.
Notably, magnesium showed potential, but due to small sample sizes and biases in the studies, we can't make firm conclusions just yet. More rigorous studies are needed to confirm these effects.
7
Magnesium shows promise for CFS
We explored the effects of magnesium on chronic fatigue syndrome (CFS), a condition marked by extended periods of debilitating fatigue. While there’s no definitive therapy established for CFS, our review of clinical trials reveals that magnesium treatment has shown promise, enhancing the well-being of some patients.
Other treatments like acyclovir have proven ineffective, and although intravenous immunoglobulin therapy shows potential, its results remain debated. We recognize that restoring immune function may be a piece of the puzzle, but overall, the effectiveness of magnesium for treating CFS symptoms is yet to be firmly established.
Other treatments like acyclovir have proven ineffective, and although intravenous immunoglobulin therapy shows potential, its results remain debated. We recognize that restoring immune function may be a piece of the puzzle, but overall, the effectiveness of magnesium for treating CFS symptoms is yet to be firmly established.
8
Magnesium potentially benefits CFS patients
We investigated the relationship between magnesium levels in red blood cells and chronic fatigue syndrome (CFS). A case-control study revealed that CFS patients had lower magnesium levels than healthy individuals.
In a randomized, double-blind trial, 32 CFS patients received either magnesium sulphate or a placebo for six weeks. Those treated with magnesium reported significant improvements in energy, emotional wellbeing, and pain relief, with twelve out of fifteen feeling better.
In contrast, only three out of seventeen patients on placebo reported any improvement. Overall, these findings suggest that magnesium treatment may positively impact the wellbeing of those suffering from CFS.
In a randomized, double-blind trial, 32 CFS patients received either magnesium sulphate or a placebo for six weeks. Those treated with magnesium reported significant improvements in energy, emotional wellbeing, and pain relief, with twelve out of fifteen feeling better.
In contrast, only three out of seventeen patients on placebo reported any improvement. Overall, these findings suggest that magnesium treatment may positively impact the wellbeing of those suffering from CFS.
7
We investigated how magnesium levels relate to chronic fatigue by studying 93 patients with unexplained fatigue.
Around 47% of participants showed magnesium deficiency, linked to reduced plasma antioxidant capacity.
Although magnesium supplementation didn't increase blood glutathione levels, we observed improved magnesium stores and vitamin E levels.
However, this did not equate to a significant boost in antioxidant activity or a decrease in lipid vulnerability. Therefore, while magnesium may help improve some parameters, it is not a panacea for chronic fatigue syndrome.
Around 47% of participants showed magnesium deficiency, linked to reduced plasma antioxidant capacity.
Although magnesium supplementation didn't increase blood glutathione levels, we observed improved magnesium stores and vitamin E levels.
However, this did not equate to a significant boost in antioxidant activity or a decrease in lipid vulnerability. Therefore, while magnesium may help improve some parameters, it is not a panacea for chronic fatigue syndrome.
References
- Alraek T, Lee MS, Choi TY, Cao H, Liu J. Complementary and alternative medicine for patients with chronic fatigue syndrome: a systematic review. BMC Complement Altern Med. 2011;11:87. 10.1186/1472-6882-11-87
- Manuel y Keenoy B, Moorkens G, Vertommen J, Noe M, Nève J, et al. Magnesium status and parameters of the oxidant-antioxidant balance in patients with chronic fatigue: effects of supplementation with magnesium. J Am Coll Nutr. 2000;19:374.
- Takahashi H, Imai K, Katanuma A, Sugaya T, Hisano K, et al. [A case of chronic fatigue syndrome who showed a beneficial effect by intravenous administration of magnesium sulphate]. Arerugi. 1992;41:1605.
- Uchida A. [Therapy of chronic fatigue syndrome]. Nihon Rinsho. 1992;50:2679.
- Cox IM, Campbell MJ, Dowson D. Red blood cell magnesium and chronic fatigue syndrome. Lancet. 1991;337:757.
- Skalova S, Neuman D, Lnenicka P, Stekrova J. Gitelman syndrome as a cause of psychomotor retardation in a toddler. Arab J Nephrol Transplant. 2013;6:37.
- Tarello W. Chronic fatigue syndrome (CFS) associated with Staphylococcus spp. bacteremia, responsive to potassium arsenite 0.5% in a veterinary surgeon and his coworking wife, handling with CFS animal cases. Comp Immunol Microbiol Infect Dis. 2001;24:233.
